Collagen HA

Please note the following referenced scientific research is for informational use only. The results reported below may not necessarily occur in all our customers. The information should not replace advice from your health care practitioner. This information should not be read to recommend or endorse any specific product.

Hair and skin are made of connective tissue which is constantly in a cycle of renewal as old cells are shed and new cells are grown to replace them. Collagen is the main structural protein in connective tissue important to support healthy skin, hair and nails. Our bodies can naturally synthesise collagen by combining amino acids from protein with essential vitamins and minerals yet external factors including aging processes, UV radiation, poor dietary intake and lack of nutrition, hormonal health, alcohol and cigarettes can affect healthy hair skin and nails.

Skin Health

  • Studies suggest collagen may be effective to improve hydration, elasticity, and wrinkling in human skin (Kim et al. 2018). 

  • Oral intake of specific bioactive collagen peptides (Verisol) reduces skin wrinkles and has positive effects on dermal matrix synthesis (Proksch 2014). 

  • Collagen peptides may support aging skin, including skin dryness (Asserin et al. 2015).

  • Collagen shows to have effect on skin fibroblasts, helping aid with the skin restoration process (Lupu et al. 2020). 

  • Collagen stimulates skin cells to produce more collagen and promote changes in the structure of the skin, delaying the signs of aging by smoothing the formation of wrinkles and improving the elasticity and firmness of skin (Gelita 2020).

  • Research indicates that 100-200mg/day of high molecular weight hyaluronic (HMW-HA) significantly improves skin hydration, brightness, and dermal density in both young and elderly groups after 2–8 weeks. After 12 weeks, it also promotes increased epidermis thickness, providing strong evidence for the clinical benefits of oral HA for skin health (Gao et al. 2023).

  • After 12 weeks of oral hyaluronic acid (MW 2 k or 300 k) suppresses wrinkles, significantly decreases wrinkle volume ratio after 8 weeks, and improves skin luster and suppleness, highlighting its potential for maintaining healthy skin (Oe et al. 2017).

Hair health

  • Collagen is the main structural protein in connective tissue and a lack of collagen can lead to a variety of health problems including weak and brittle hair (Green Dispensary 2020). 

  • Marine collagen may show to have hair growth promoting benefits (Kim & Kim 2017), (Kim et al. 2017).

Nail Health

  • Studies support the daily ingestion of collagen increases nail growth and improves brittle nails (Hexsel et al. 2017). 

  • Collagen may have a positive impact on nail improvement, quality and growth (Moskowitx 2000). 

  • Marine collagen acts to protect skin cells and tissue due to its antioxidant activity and may correct damage caused to skin, hair and nails (Venugopal 2008).

References

  • Kim, DU., Chung, HC., Choi. J., Sakai, Y., Lee, BY. 2018. “Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study”. Nutrients. 26. 10(7):826. doi: 10.3390/nu10070826. 

  • Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., Oesser, S. 2014. “ Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis”. Skin Pharmacol Physiol, 27(3):113-9. doi: 10.1159/000355523.

  • Asserin, J., Lati, E., Shioya, T., Prawitt, J. 2015. “ The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials”. J Cosmet Dermatol. 14(4):291-301. doi: 10.1111/jocd.12174.

  • Hexsel, D., Zague, V., Schunck, M., Siega, C., Camozzato, FO., Oesser, S. 2017. “Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails”. J Cosmet Dermatol. 16(4):520-526. doi: 10.1111/jocd.12393. 

  • Lupu, M.A, Gradisteanu Pircalabioru, G., Chifiriuc, MC., Albulescu, R., Tanase, C. 2020  “Beneficial effects of food supplements based on hydrolyzed collagen for skin care (Review)”. Exp Ther Med. 20(1):12-17. doi: 10.3892/etm.2019.8342. 

  • 2020. Verisol Bioactive Collagen Peptides. Gelita. https://www.gelita.com/en 

  • Kim, B. Y., & Kim, H. S. 2017. “Successful hair regrowth in a Korean patient with alopecia universalis following tofacitinib treatment”. Singapore medical journal, 58(5), 279–280. https://doi.org/10.11622/smedj.2017039

  • Kim, S., Ravichandran, Y.D., Khan, S.B. 2017. “Prospective of the cosmeceuticals derived from marine organisms”. Biotechnol Bioproc E. 13, 511–523. https://doi.org/10.1007/s12257-008-0113-5

  • 2020. The “Beauty” of Collagen. Green Dispensary. https://greendispensary.com.au/the-beauty-of-collagen/ 

  • Moskowitz, RW. 2000. “Role of collagen hydrolysate in bone and joint disease”. Semin Arthritis Rheum.30(2):87-99. doi: 10.1053/sarh.2000.9622.

  • Benugopal, V. 2008. Marine sources of vitamins and minerals in marine products for healthcare. Fl: CRC Press.

  • Gao, Y. R., Wang, R. P., Zhang, L., Fan, Y., Luan, J., Liu, Z., & Yuan, C. 2023. "Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test." Skin Res Technol, 29(11), e13531. https://doi.org/10.1111/srt.13531

  • Oe M, Sakai S, Yoshida H, Okado N, Kaneda H, Masuda Y, Urushibata O. 2017. "Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period." Clin Cosmet Investig Dermatol. Jul 18;10:267-273. doi: 10.2147/CCID.S141845.