Please note the following referenced scientific research is for informational use only.
The results reported below may not necessarily occur in all our customers.
The information should not replace advice from your health care practitioner.
This information should not be read to recommend or endorse any specific product.
Curcumin is the most active constituent in turmeric and is known for its powerful anti-inflammatory and antioxidant properties.
This golden root is a cousin to ginger and has a long history of traditional use in Chinese and Indian (Ayurvedic) medicine. Curcumin acts as a master switch of inflammation literally blocking and interfering with the inflammatory response pathways in the body and offering a protective effect.
Joint Health
Curcumin has been found to be effective in improving joint swelling and pain (Chandran & Goel 2012).
Due to curcumins anti-inflammatory properties, it has shown to reduce joint aches and pain (Gupta et al. 2013).
Reduces joint pain in patients with osteoarthritis via anti-inflammatory mechanisms (Chin 2016).
Curcumin has shown to have anti-arthritic effects on chronic inflammatory joint conditions (Hewlings & Kalman 2017).
Anti-inflammatory
Strong evidence confirms the anti-inflammatory activity of curcumin and its potency to target inflammatory diseases (Braun & Cohen 2015, 1010).
Curcumin acts as a master switch of inflammation on pro-inflammatory enzymes and transcription factors (Jurenka 2009).
Curcumin has been shown to supress inflammation through many mechanisms (Hewlings & Kalman 2017).
Antioxidant
Studies confirm the potent antioxidant activity curcumin shows. It exerts direct free radical scavenging activity and enhances antioxidant activity (Braun & Cohen 2015, 1010).
Curcumin improves systemic markers of oxidative stress (Hewlings & Kalman 2017).
Curcumins antioxidant activity is more potent than that of ascorbic acid or resveratrol and can increase activities of other antioxidants like superoxide dismutase (SOD) (Hewlings & Kalman 2017).
Digestion & Liver Health
Curcumin has been found to modulate gut microbiota, helping to prevent gut dysbiosis and promoting overall digestive health (Zhu & He 2024).
Curcumin has been shown to directly regulate gut microbiota by increasing beneficial bacteria like bifidobacteria, lactobacilli, and butyrate producers, while reducing harmful microbes, which may explain its immune-modulating, antihyperlipidemic, anti-inflammatory, and anticancer effects (Zam 2018).
For liver health, curcumin has been studied for its hepatoprotective properties, which include its ability to reduce liver inflammation, combat oxidative stress, and support liver function by enhancing detoxification pathways. Research has shown that curcumin helps protect liver cells from damage caused by toxins and improves overall liver function (Abe et al. 1999).
References
Braun, L., and Cohen,Marc. 2015. Herbs & Natural Supplements An Evidence-based guide Volume 2. 4th ed. Australia: Elsevier.
Jurenka, JS. 2009. “Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research.” Alternative medicine review: A journal of clinical therapeutic 14. 2 (Jun): 41-53. https://www.ncbi.nlm.nih.gov/pubmed/19594223
Linus Pauling Institute. 2019. Micronutrient Information Center Curcumin. https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/curcumin
Chandran, B., Goel, A. 2012. “A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis.” Phytotherapy Research: PTR, 26. 11 (Nov): 1719-25. 10.1002/ptr.4639
Gupta, SC., Patchva, S., Aggarwal, BB. 2013. “Therapeutic Roles of Curcumin: Lessons learned from clinical trials.” The American Association of Pharmaceutical Scientists, 15. 1 (Jan): 195-218. 10.1208/s12248-012-9432-8
Chin, KY. 2016. “The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis.” Drug Design, Development and Therapy. 10: (3029-3042). 10.2147/DDDT.S117432
Hewlings, SJ., Kalman, DS. 2017. “Curcumin: A Review of It’s Effects on Human Health.” Foods, 6. 10 (Oct): 92. doi:10.3390/foods6100092
Zhu, Junwen, and He, Lan. 2024. "The Modulatory Effects of Curcumin on the Gut Microbiota: A Potential Strategy for Disease Treatment and Health Promotion" Microorganisms 12, no. 4: 642. https://doi.org/10.3390/microorganisms12040642
Abe Y, Hashimoto S, Horie T 1999. "Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages." Pharmacol Res 39(1):41–47. https://doi.org/10.1006/phrs.1998.0404
Zam W. 2018. Gut Microbiota as a Prospective Therapeutic Target for Curcumin: A Review of Mutual Influence. Journal of nutrition and metabolism, 1367984. https://doi.org/10.1155/2018/1367984